Antigen-specific induction of IL-17 cytokines leads to proinflammatory responses in various autoimmune diseases. Here, we have provided a machine learning based tool for predicting IL-17 inducing response of any peptide/protein antigen.

To assist users, we have incorporated following section/tools in this web server:
  • Peptide prediction: In this section, user can submit peptide of 5-30 amino acid length and can predict the IL-17 inducing property of peptides.
  • Protein Scan: This tool enables user to identify IL-17 inducing regions in a full length protein/amino acid sequence. Here user can select desired length of peptide for prediction.
  • Epitope Mapping: To assist user mapping experimentally validated IL-17 inducing epitopes on its query sequence, we have provided this tool. In this tool user can get the query mapped with IL-17 inducing epitopes and links to related assay in IEDB database.
  • Similarity Search: In contrast to the epitope mapping module where exact matches with experimental data is seen, this tool performs Smith Watermann search of query sequence in database of experimentally validated IL-17 inducing epitopes.